This is an historical archive of the activities of the MRC Anatomical Neuropharmacology Unit (MRC ANU) that operated at the University of Oxford from 1985 until March 2015. The MRC ANU established a reputation for world-leading research on the brain, for training new generations of scientists, and for engaging the general public in neuroscience. The successes of the MRC ANU are now built upon at the MRC Brain Network Dynamics Unit at the University of Oxford.

News- Basal Ganglia Labs present at summer conferences.

Members of the basal ganglia laboratories have presented at several international meetings over the summer.

IBAGS X (Tenth Triennial Meeting of the International Basal Ganglia Society) Long Branch, New Jersey (June 20th-24th).

Juan Mena-Segovia gave one of the lectures entitled 'Functional diversity in the pedunculopontine neurons that project to the basal ganglia: Implications for Parkinson's disease'

Unit members presented the following posters:

Doig, N.M., Moss, J & Bolam, J.P. (2010) Cortical and thalamic innervation of direct and indirect pathway medium-sized spiny neurons in mouse striatum. P-55

Ellender, T.J., Huerta-Ocampo, I., Capogna, M & Bolam, J.P. (2010) Histaminergic modulation of striatal function. P-90

Henny, P., Brown, M.T.C., Northrop, A., Micklem, B.R., Magill, P.J & Bolam, J.P. (2010) Structural bases of activity of identified dopaminergic neurons in the substantia nigra pars compacta. P-71

Huerta-Ocampo, I., Mena-Segovia, J & Bolam, J.P. (2010) In vivo characterization of direct and indirect medium sized spiny neurons (MSNs) located in the striatal matrix compartment and their innervation by cortical and thalamic afferents. P-15

Mallet, N., Micklem, B.R., Henny, P., Brown, M.T.C., Williams, C., Bolam, J.P & Magill, P.J. (2010) Elucidating functional dichotomy in the external globus pallidus: A major population of pallidal neurons specifically innervated striatum. P-84

Martinez-Gonzalez, C., Bolam, J.P & Mena-Segovia, J. (2010) Neurons containing calcium binding proteins are topographically organised in the pedunculopontine. P-173

Moss, J & Bolam, J.P. (2010) Anatomical analyses of glutamatergic and dopaminergic synapses of the rat striatum. P-171

Nakamura, K.C and Magill, P.J. (2010) Spontaneous activity of neurons in basal ganglia and cerebellar-recipient zones of the rat motor thalamus in vivo. P-96

Pienaar, I.S., Micklem, B.R., Martinez-Gonzalez, C., Stewart, R., Bolam. J.P & Mena-Segovia, J. (2010) Stereological estimation of the total number of neurons in the pedunculopontine nucleus and their topographical distribution. P-87

Pissadaki, E. K. & Bolam, J.P. (2010) Signal propagation and metabolic efficiency in the axons of the SNc dopamine neurons. P-115

Physiological Society Meeting in Manchester (30th June-2nd July)Paul Bolam gave a lecture entitled 'New results on thalamostriatal projections and their relationship with dopaminergic afferents' in a symposium at the Physiological Society Meeting in Manchester, "From striatal circuits to basal ganglia function: how recent experimental findings constrain our models"

7th Meeting of FENS (Amsterdam, July 3rd to 7th)Paul Bolam organised and chaired a symposium : "Select and Act: The role of the striatum in selection of behaviour". Peter Magill gave one of the lectures entitled 'Synchronised oscillations in the striato-pallidal network'. The symposium was attended by about 700 people

Members of several Unit labs presented posters at the meeting:

Bienvenu, T., Busti, D., Magill, P.J., Ferraguti, F. & Capogna, M. (2010) GABAergic cell types of the basolateral amygdala are differently modulated by hippocampal theta oscillations and noxious stimuli. 130.7

Dupret, D., O'Neill, J. Pleydell-Bouverie, B. & Csicsvari, J. (2010) Hippocampal population representation during a matching-to-multiple-places task. 025.12Hartwich, K., Massi, L. & Klausberger, T. (2010) Brain state dependent firing patterns of identified interneurons in the medial prefrontal cortex. 130.30

Lapray, D., Asede, D., Szabo, A., Nissen, W., Capogna, M., Somogyi, P. & Lamsa, K. (2010) Axonal variability of GABAergic ivy interneurons in the hippocampal CA1 area. 104.10

Lasztóczi, B. Tukker, J.J., Lapray, D., Klausberger, T. & Somogyi, P. (2010) Spike-timing of cholecystokinin containing hippocampal CA3 interneurons in relation to physiological network oscillations in vivo. 130.44

Magill, P.J., Sharott, A. & Mallet, N. (2010) Synchronised oscillations in the striatopallidal network. 122.2

Manko, M., Geracitano, R., & Capogna, M. (2010) The role of main intercalated nucleus of the mouse amygdala. 075.24

O'Neill, J., Pleydell-Bouverie, B., O'Neill, J. & Dupret, D. (2010) Oscillatory coupling between the hippocampus and medial entorhinal cortex during a working memory task. 087.14Pleydell-Bouverie, B., O'Neill, J., Dupret, D., Paulsen, O. & Csicsvari, J. (2010) Sharp wave events coordinate information transfer in the hippocampal-entorhial system during sleep but not during exploration. 087.18GABA Signalling and Brain Networks (FENS Satellite)Peter Magill attended and gave a lecture entitled 'Disturbed network activities of GABAergic basal ganglia projection neurons in Parkinsonism 'at a satellite symposium of the FENS meeting, an EMBO Workshop, "GABA Signalling and Brain Networks".

Slow Brain Oscillations of Sleep, Resting State and Vigilance (FENS Satellite)Juan Mena-Segovia gave a lecture entitled 'Impact of brainstem network activity on cortical dynamics during slow oscillations' at a satellite symposium of the FENS meeting (26th International Summer School of Brain Research on "Slow brain oscillations of sleep, resting state and vigilance"), organised by the Netherlands Institute for Neuroscience.

38th Meeting of European Histamine Research SocietyTommas Ellender presented a poster entitled "Histaminergic modulation of striatal function" at the 38th Meeting of European Histamine Research Society. This meeting was one of the casualties of the Icelandic volcanic ash earlier this year!