Neuropeptide signalling in health and disease.
Professor Tomas Hökfelt, Department of Neuroscience, Karolinska Institutet, Stockholm, (http://ki.se/ki/jsp/polopoly.jsp?d=25981&a=55039&l=en) delivered the 8th David Smith Lecture on the 21st May 2013, followed by dinner at Lady Margaret Hall.
Professor Hökfelt is one the fathers of the field of neuropeptide research. His research focuses on the localization and function of neuropeptides in the healthy and diseased brain. He talked about three of the neuropeptide systems he had worked on, how neuropeptides or neuropeptide receptors could be novel therapeutic targets in the treatment of pain, insomnia and anxiety/depression, but how early hopes had not come to fruition. He finished on a note of optimism for future research on neuropeptides and new therapeutic targets.
The Lecture each year celebrates the vision of the previous Chair of Pharmacology and founding Director of the Unit, Prof. A. David Smith, currently Honorary Associate Director and Emeritus Professor, and the successful conclusion of the last quinquennial scientific review of the Unit.
To commemorate the lecture Prof. Hökfelt received a laser-engraved cherry-wood plaque, designed by Unit Artist, Ben Micklem, illustrating aspects of Anatomical Neuropharmacology at Oxford from molecules to the brain.
Cell-type specific regulation of interneuronal microcircuits in the cortex
Professor Ivan Soltesz, Department of Anatomy and Neurobiology, University of California Irvine. http://www.anatomy.uci.edu/soltesz.html delivered the 7th David Smith Lecture on the 6th March 2012, followed by dinner at Brasenose College.
Professor Jean-Marc Fritschy delivered the 11th David Smith Lecture in Anatomical Neuropharmacology.
"Plasticity of GABAergic synapses: mechanisms and implications"
The 11th David Smith Lecture in Anatomical Neuropharmacology was given on 3 March 2015 by Professor Jean-Marc Fritschy of the Institute of Pharmacology and Toxicology at the University of Zurich http://www.pharma.uzh.ch/neuromorpho
The Lecture was hosted by Professor Peter Somogyi.
Glutamate receptors: their localization, function, and roles in physiological learning processes
The 4th David Smith Lecture in Anatomical Neuropharmacology was given on the 4th May, by Prof. Ryuichi Shigemoto, Head of Division of Cerebral Structure, National Institute for Physiological Sciences, Okazaki, Japan, and Professor, National Institute for Physiological Sciences, The Graduate University for Advanced Studies, School of Life Science.
Habits, Rituals, and the Evaluative Brain
The 5th David Smith Lecture in Anatomical Neuropharmacology was given on the 21st September, by Prof. Ann Graybiel, McGovern Institute, MIT, Cambridge, USA.
The lecture was set up to celebrate the vision of the previous Chair of Pharmacology Prof. A. David Smith, Honorary Associate Director and founder of the Unit, and the successful conclusion of the latest quinquennial scientific review of the Unit.
Functional properties of fast spiking GABAergic interneurons in thehippocampal network.Prof. Peter Jonas, Institute of Science and Technology (IST), Vienna, Austria.