Julia Gottwald has joined Dr Marco Capogna’s group to perform an experimental project in Hilary Term as MSc Neuroscience student. Julia was born in Germany and received a BSc in Biochemistry (with Distinction) at the Free University in Berlin.She has some previous lab experience at the Max Delbruck Center for Molecular Medicine in Berlin, and at the Max Planck Institute for Neurobiology in Munich. Her project aims to investigate the cellular mechanisms underlying the reduction of theta-dominant neuronal oscillations in response to aversive cues in transgenic mice expressing high level of the serotonin transporter (5-HTT OE). She will be studying the cell firing and synaptic transmission, with particular reference to oscillatory activity, in the acute slices of amygdala of wild type and 5-HTT OE mice. This investigation is potentially interesting for fundamental neuroscience, since the serotonin transporter regulates the intensity and duration of serotonergic neurotransmission, but also for preclinical neuroscience, since the serotonin transporter is the principal target for antidepressant and anxiolytic drugs. The electrophysiological experiments in vitro will be performed as part of a collaboration involving Dr. David Bannerman (Exp Psychology), who is testing these mice in freely moving, behaving experiments, and Prof Trevor Sharp (Pharmacology).
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