Dr Rahul Shah graduated with honours from Leicester Medical School in 2010 and joins the unit from Southampton General Hospital where he is an Academic Foundation Doctor in Neurosurgery. During his medical degree he intercalated a BSc in the Neural Plasticity Lab under Robert Pawlak, and undertook electives at the University of Cape Town and Mayo Clinic Rochester.
Rahul is undertaking a 4-month research rotation in the Magill group supervised by Dr Andrew Sharott, utilising in vivo electrophysiology to investigate properties of novel fast-spiking interneurons in the dorsolateral striatum.
Thomas David Fischer joins the Capogna lab as a student visitor to help with the anatomical characterisation of recorded neurons of the amygdala. David is a medical student at the University of Innsbruck. In Oxford, he will be also involved in clinical rotations (8 weeks each) with Prof. Chapman (Dept. Internal Medicine, John Radcliffe Hospital) and Prof. Peter Brown (Dept Clinical Neurology, John Radcliffe Hospital) supported by the Erasmus Program.
We are pleased to welcome Dr. Todor Gerdjikov from Leicester University for a sabbatical leave in the Unit. In collaboration with Dr Juan Mena-Segovia, Dr. Gerdjikov will develop a project aiming to identify the functional connectivity between cholinergic and dopaminergic structures during behavioural tasks.
Dr Melanie Ludlow has joined the McIlhinney group for two years to investigate potential modulator binding sites on the AMPA receptor. Following on from her PhD studies Melanie has just completed a post-doctoral position at Leicester University, studying the function of P2X receptors in Dictyostelium discoideum.
We are pleased to welcome Michael Crump as a visiting student to Professor Somogyi's lab. Michael has just graduated from University of Leeds where he did BSc Neuroscience and spent his industrial placement year working in the laboratory of Dr Steven Younkin at the Mayo Clinic Florida (http://www.mayoclinic.org/jacksonville/). He will become a Probationary Research Student studying towards a DPhil from October 2010 and explore septo-hippocampal relationships under the joint supervision of Peter Somogyi and Damien Lapray.
Limbic encephalitis (LE) is a CNS disease characterized by subacuteonset of memory loss and epileptic seizures. The paper shows that LEantibodies enhance the excitability of hippocampal CA3 pyramidal cellsproviding a cellular mechanism for the disease phenotype. This resulthas been obtained through a collaborative effort between group of MarcoCapogna, at our MRC Unit and the group of Angela Vincent at theWeatherall Institute of Molecular Medicine of the John Radcliffe Hospital.