Anatomical Neuropharmacology Unit

This is an historical archive of the activities of the MRC Anatomical Neuropharmacology Unit (MRC ANU) that operated at the University of Oxford from 1985 until March 2015. The MRC ANU established a reputation for world-leading research on the brain, for training new generations of scientists, and for engaging the general public in neuroscience. The successes of the MRC ANU are now built upon at the MRC Brain Network Dynamics Unit at the University of Oxford.

Publications

2002

Unit Publication
Fujiyama F, Stephenson AF, Bolam JP. Synaptic localization of GABA(A) receptor subunits in the substantia nigra of the rat: effects of quinolinic acid lesions of the striatum. Eur J Neurosci. 2002;15(12):1961-75.PDF icon FujiyamaJNeurosci2002.pdf (1.33 MB)
Unit Publication
Jones IW, Bradly A, Bolam JP, Wonnacott S. Localisation of neuronal nicotinic acetylcholine receptor subunits in rat substantia nigra and dorsal striatum.. 2002.
Unit Publication
Klausberger T, Roberts DJ, Somogyi P. Cell type- and input-specific differences in the number and subtypes of synaptic GABA(A) receptors in the hippocampus. J Neurosci. 2002;22(7):2513-21.PDF icon KlausbergerNeurosci.pdf (912.86 KB)

2001

Unit Publication
Pike F, Molden S, Paulsen O, Moser EI. Synaptic potentiation by natural patterns of activity in the hippocampus.. 2001.
Unit Publication
Szabadics J, Lorincz A, Tamás G. Beta and gamma frequency synchronization by dendritic gabaergic synapses and gap junctions in a network of cortical interneurons. J Neurosci. 2001;21(15):5824-31.
Unit Publication
A Becher, White JH, McIlhinney RA. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 2001;79(4):787-95.PDF icon BecherJNeurochem2001.pdf (580.29 KB)
Unit Publication
Tretter V, Hauer B, Nusser Z, Mihalek RM, Höger H, Homanics GE, et al. Targeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cells. J Biol Chem. 2001;276(13):10532-8.PDF icon TretterJBiolChem.pdf (316.92 KB)
Unit Publication
Billinton A, Ige AO, Bolam JP, White JH, Marshall FH, Emson PC. Advances in the molecular understanding of GABA(B) receptors. Trends Neurosci. 2001;24(5):277-82.PDF icon billinton2001tins.pdf (409.91 KB)
Unit Publication
Wolfart J, Neuhoff H, Franz O, Roeper J. Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons. J Neurosci. 2001;21(10):3443-56.PDF icon wolfart2001jneurosci.pdf (3.92 MB)
Unit Publication
Jones IW, Bolam JP, Wonnacott S. Presynaptic localisation of the nicotinic acetylcholine receptor beta2 subunit immunoreactivity in rat nigrostriatal dopaminergic neurones. J Comp Neurol. 2001;439(2):235-47.PDF icon JonesJCompNeuro2001.pdf (904.19 KB)
Unit Publication
Chan WY, Soloviev MM, Ciruela F, McIlhinney RA. Molecular determinants of metabotropic glutamate receptor 1B trafficking. Mol Cell Neurosci. 2001;17(3):577-88.PDF icon ChanMolCellNeurosci2001.pdf (572.74 KB)
Unit Publication
Ciruela F, Escriche M, Burgueno J, Angulo E, Casado V, Soloviev MM, et al. Metabotropic glutamate 1alpha and adenosine A1 receptors assemble into functionally interacting complexes. J Biol Chem. 2001;276(21):18345-51.PDF icon CiruelaJBioChem2001.pdf (1.11 MB)
Unit Publication
Ciruela F, McIlhinney RA. Metabotropic glutamate receptor type 1alpha and tubulin assemble into dynamic interacting complexes. J Neurochem. 2001;76(3):750-7.PDF icon CiruelaJNeurochem2001.pdf (568.02 KB)
Unit Publication
Fisahn A, Buhl EH. A role of kainate receptors in the induction of gamma frequency oscillations in the rodent somatosensory cortex in vitro.. 2001.
Unit Publication
Ginham R, Harrison DC, Facci L, Skaper S, Philpott KL. Upregulation of death pathway molecules in rat cerebellar granule neurons undergoing apoptosis. Neurosci Lett. 2001;302(2-3):113-6.PDF icon ginham_2001.pdf (136.05 KB)
Unit Publication
Liss B, Franz O, Sewing S, Bruns R, Neuhoff H, Roeper J. Tuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcription. EMBO J. 2001;20(20):5715-24.PDF icon LissEMBO2001.pdf (424.6 KB)
Unit Publication
Liss B, Roeper J. ATP-sensitive potassium channels in dopaminergic neurons: transducers of mitochondrial dysfunction. News Physiol Sci. 2001;16:214-7.PDF icon LissPhysiolSci2001.pdf (457.29 KB)
Unit Publication
Liss B, Roeper J. Molecular physiology of neuronal K-ATP channels (review). Mol Membr Biol. 2001;18(2):117-27.PDF icon LissMoleMemBio2001.pdf (494.68 KB)
Unit Publication
Magill PJ, Bolam JP, Bevan MD. Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network. Neuroscience. 2001;106(2):313-30.PDF icon Magill2001.pdf (4.95 MB)
Unit Publication
Meddows E, Le Bourdelles B, Grimwood S, Wafford K, Sandhu S, Whiting P, et al. Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptors. J Biol Chem. 2001;276(22):18795-803.PDF icon MeddowsJBiolChem.pdf (417.49 KB)
Unit Publication
Miki T, Liss B, Minami K, Shiuchi T, Saraya A, Kashima Y, et al. ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis. Nat Neurosci. 2001;4(5):507-12.PDF icon miki2001natneurosci.pdf (208.27 KB)
Unit Publication
Nyíri G, Freund TF, Somogyi P. Input-dependent synaptic targeting of alpha(2)-subunit-containing GABA(A) receptors in synapses of hippocampal pyramidal cells of the rat. Eur J Neurosci. 2001;13(3):428-42.PDF icon NyiriEurJNeurosci.pdf (964.32 KB)

2000

Unit Publication
Ciruela F, Soloviev MM, Chan WY, McIlhinney RA. Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function. Mol Cell Neurosci. 2000;15(1):36-50.PDF icon CiruelaMolCellNeuro2000.pdf (874.78 KB)
Unit Publication
White JH, McIlhinney RA, Wise A, Ciruela F, Chan WY, Emson PC, et al. The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx. Proc Natl Acad Sci USA. 2000;97(25):13967-72.
Unit Publication
Fassio A, Evans G, Grisshammer R, Bolam JP, Mimmack M, Emson PC. Distribution of the neurotensin receptor NTS1 in the rat CNS studied using an amino-terminal directed antibody. Neuropharmacology. 2000;39(8):1430-42.PDF icon FassioNeuropharm2000.pdf (2.18 MB)

Pages