Anatomical Neuropharmacology Unit

This is an historical archive of the activities of the MRC Anatomical Neuropharmacology Unit (MRC ANU) that operated at the University of Oxford from 1985 until March 2015. The MRC ANU established a reputation for world-leading research on the brain, for training new generations of scientists, and for engaging the general public in neuroscience. The successes of the MRC ANU are now built upon at the MRC Brain Network Dynamics Unit at the University of Oxford.

Publications

2007

Unit Publication
Tepper JM, Abercrombie ED, Bolam JP. GABA and the Basal Ganglia: From Molecules to Systems. Vol 160. Elsevier Science; 2007.
Unit Publication
Wulff P, Goetz T, Leppä E, Linden A-, Renzi M, Swinny JD, et al. From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors. Nat Neurosci. 2007;10(7):923-9.PDF icon wulff2007natneurosci.pdf (1.93 MB)
Unit Publication
Pooler AM, McIlhinney RA. Lateral diffusion of the GABAB receptor is regulated by the GABAB2 C terminus. J Biol Chem. 2007;282(35):25349-56.PDF icon pooler2007jbiochem.pdf (787.78 KB)
Unit Publication
Tukker JJ, Fuentealba P, Hartwich K, Somogyi P, Klausberger T. Cell type-specific tuning of hippocampal interneuron firing during gamma oscillations in vivo. J Neurosci. 2007;27(31):8184-9.PDF icon tukker2007jneurosci.pdf (407.1 KB)
Unit Publication
Cabello N, Remelli R, Canela L, Soriguera A, Mallol J, Canela EI, et al. Actin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor. J Biol Chem. 2007;282(16):12143-53.PDF icon cabello2007jbiochem.pdf (664.88 KB)
Unit Publication
Csicsvari J, O'Neill J, Allen K, Senior T. Place-selective firing contributes to the reverse-order reactivation of CA1 pyramidal cells during sharp waves in open-field exploration. Eur J Neurosci. 2007;26(3):704-16.PDF icon csicsvari2007ejn.pdf (2.63 MB)
Unit Publication
Geracitano R, Kaufmann WA, Szabo G, Ferraguti F, Capogna M. Synaptic heterogeneity between mouse paracapsular intercalated neurons of the amygdala. J Physiol (Lond). 2007;585(Pt 1):117-34.PDF icon geracitano2007jphysiol.pdf (1.2 MB)
Unit Publication
Lemon R, Bolam JP. Motor systems. Curr Opin Neurobiol. 2007;17(6):619-21.PDF icon lemon2007currentopinionneurobiol.pdf (79.16 KB)
Unit Publication
Karayannis T, Huerta-Ocampo I, Capogna M. GABAergic and pyramidal neurons of deep cortical layers directly receive and differently integrate callosal input. Cereb Cortex. 2007;17(5):1213-26.PDF icon karayannis2007cerebcortex.pdf (1.12 MB)
Unit Publication
Temel Y, Boothman LJ, Blokland A, Magill PJ, Steinbusch HW, Visser-Vandewalle V, et al. Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus. Proc Natl Acad Sci USA. 2007;104(43):17087-92.PDF icon temel2007pnas.pdf (901.25 KB)
Unit Publication
Kerr AM, Capogna M. Unitary IPSPs enhance hilar mossy cell gain in the rat hippocampus. J Physiol (Lond). 2007;578(Pt 2):451-70.PDF icon kerr2007jphysiol.pdf (9.41 MB)
Unit Publication
Jeans AF, Oliver PL, Johnson R, Capogna M, Vikman J, Molnár Z, et al. A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse. Proc Natl Acad Sci USA. 2007;104(7):2431-6.PDF icon jeans2007pnas.pdf (1.08 MB)
Unit Publication
Baude A, Bleasdale C, Dalezios Y, Somogyi P, Klausberger T. Immunoreactivity for the GABAA receptor alpha1 subunit, somatostatin and Connexin36 distinguishes axoaxonic, basket, and bistratified interneurons of the rat hippocampus. Cereb Cortex. 2007;17(9):2094-107.PDF icon baude2007cerebralcortex.pdf (2.47 MB)
Unit Publication
Lacey CJ, Bolam JP, Magill PJ. Novel and distinct operational principles of intralaminar thalamic neurons and their striatal projections. J Neurosci. 2007;27(16):4374-84.PDF icon lacey207jneurosci.pdf (922.86 KB)
Unit Publication
Esapa CT, Waite A, Locke M, Benson MA, Kraus M, McIlhinney RA, et al. SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA. Hum Mol Genet. 2007;16(3):327-42.PDF icon esapa2007humanmolgen.pdf (1.63 MB)
Unit Publication
Boyes J, Bolam JP, Shigemoto R, Stanford IM. Functional presynaptic HCN channels in the rat globus pallidus. Eur J Neurosci. 2007;25(7):2081-92.PDF icon boyes2007ejn.pdf (1.48 MB)
Unit Publication
Tepper JM, Abercrombie ED, Bolam JP. Basal ganglia macrocircuits. Prog Brain Res. 2007;160:3-7.
Unit Publication
Boyes J, Bolam JP. Localization of GABA receptors in the basal ganglia. Prog Brain Res. 2007;160:229-43.
Unit Publication
Jinno S, Klausberger T, Marton LF, Dalezios Y, Roberts DJ, Fuentealba P, et al. Neuronal diversity in GABAergic long-range projections from the hippocampus. J Neurosci. 2007;27(33):8790-804.PDF icon jinno2007jneurosci.pdf (5 MB)
Unit Publication
Lamsa KP, Heeroma JH, Somogyi P, Rusakov DA, Kullmann DM. Anti-Hebbian long-term potentiation in the hippocampal feedback inhibitory circuit. Science. 2007;315(5816):1262-6.PDF icon lamsa2007science.pdf (2.63 MB)
Unit Publication
Agid Y, Buzsáki G, Diamond DM, Frackowiak R, Giedd J, Girault J-, et al. How can drug discovery for psychiatric disorders be improved? Nat Rev Drug Discov. 2007;6(3):189-201.PDF icon agrid2007natreviewsdrugdiscovery.pdf (1.37 MB)
Unit Publication
Sadek AR, Magill PJ, Bolam JP. A single-cell analysis of intrinsic connectivity in the rat globus pallidus. J Neurosci. 2007;27(24):6352-62.PDF icon sadek2007jneurosci.pdf (2.04 MB)
Unit Publication
Atlason PT, Garside ML, Meddows E, Whiting P, McIlhinney RA. N-Methyl-D-aspartate (NMDA) receptor subunit NR1 forms the substrate for oligomeric assembly of the NMDA receptor. J Biol Chem. 2007;282(35):25299-307.PDF icon atlason2007jbiochem.pdf (601.92 KB)

2006

Unit Publication
Pontier SM, Lahaie N, Ginham R, St-Gelais F, Bonin H, Bell DJ, et al. Coordinated action of NSF and PKC regulates GABAB receptor signaling efficacy. EMBO J. 2006;25(12):2698-709.PDF icon Pontier et al. (2006) EMBO J. (338.17 KB)
Unit Publication
Magill PJ, Pogosyan A, Sharott A, Csicsvari J, Bolam JP, Peter Brown. Changes in functional connectivity within the rat striatopallidal axis during global brain activation in vivo. J Neurosci. 2006;26(23):6318-29.PDF icon magill2006jneurosci.pdf (2.14 MB)

Pages